MATERIAL SAFETY DATA SHEET (SDS)

1. Identification

Product Name: NAD+ 500mg (Nicotinamide Adenine Dinucleotide, oxidized form).
Restrictions on Use: For research and laboratory use only. Not intended for human or animal
diagnostic or therapeutic uses.

2. Hazard(s) Identification

Classification: Based on available information, this substance is not expected to be classified
as a hazardous chemical under normal laboratory handling conditions (e.g., GHS classification not established or
not classified as hazardous).

Potential Health Effects: While not acutely toxic, fine dust may cause mechanical irritation to
the eyes, skin, and respiratory tract. Overexposure to dust should be avoided.

3. Composition / Information on Ingredients

Substance Name: Nicotinamide Adenine Dinucleotide (oxidized form)
Purity/Concentration: Supplier to confirm (typically ≥ 95% for laboratory grade).
Impurities: Not established. Supplier to confirm presence of any hazardous impurities.

4. First-Aid Measures

• Inhalation: If dust is inhaled, move person to fresh air. If not breathing or breathing is
  difficult, seek medical attention.
• Skin Contact: Wash off with soap and plenty of water. Remove contaminated clothing. Seek
  medical advice if irritation develops.
• Eye Contact: Flush eyes with copious amounts of water for at least 15 minutes as a precaution.
  Seek medical attention if irritation persists.
• Ingestion: Rinse mouth with water. Never give anything by mouth to an unconscious person. Do
  not induce vomiting without medical advice. Seek medical advice.

5. Fire-Fighting Measures

Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.

Specific Hazards: Carbon oxides, nitrogen oxides (NOx), oxides of phosphorus may be formed under
fire conditions.

Fire-Fighting Instructions: Wear self-contained breathing apparatus (SCBA) and standard
structural firefighter protective clothing if necessary.

6. Accidental Release Measures

Personal Precautions: Use personal protective equipment (see Section 8). Avoid dust formation.
Avoid breathing dust, vapors, or mist. Ensure adequate ventilation.

Environmental Precautions: Prevent further leakage or spillage if safe to do so. Do not let
product enter drains.

Clean-up Methods: Sweep up and shovel carefully to minimize dust generation. Keep in suitable,
closed containers for disposal.

7. Handling and Storage

Handling: Provide appropriate exhaust ventilation at places where dust is formed. Avoid contact
with skin and eyes. Practice good industrial hygiene.

Storage: Keep container tightly closed in a dry and well-ventilated place. Recommended storage
temperature: -20°C (Supplier to confirm specific temperature requirements). Protect from moisture and light.

8. Exposure Controls / Personal Protection

Exposure Limits: No occupational exposure limits established for this substance.

Engineering Controls: Handle in accordance with good industrial hygiene and safety practice. Use
general or local exhaust ventilation to minimize dust exposure.

Personal Protective Equipment (PPE):

• Eye Protection: Safety glasses with side-shields conforming to standard lab safety regulations.
• Hand Protection: Compatible chemical-resistant gloves (e.g., nitrile). Inspect before use.
• Skin/Body Protection: Standard laboratory coat or appropriate workwear.
• Respiratory Protection: Not generally required under normal conditions. Where dust generation
  is significant, use a certified dust mask or respirator.

9. Physical and Chemical Properties

• Appearance: White to off-white powder
• Odor: Not established
• pH: Not established
• Melting / Freezing Point: Not established
• Initial Boiling Point: Not applicable for solid
• Flash Point: Not applicable
• Flammability (solid, gas): Not available
• Solubility: Soluble (or expected to be soluble) in water
• Partition Coefficient (n-octanol/water): Not available
• Auto-ignition Temperature: Not available

10. Stability and Reactivity

Reactivity: No data available.

Chemical Stability: Stable under recommended storage conditions.

Possibility of Hazardous Reactions: Not established.

Conditions to Avoid: Avoid moisture, exposure to light, and elevated temperatures.

Incompatible Materials: Strong oxidizing agents.

Hazardous Decomposition Products: Formed under fire conditions: Carbon oxides, Nitrogen oxides,
Phosphorus oxides.

11. Toxicological Information

Acute Toxicity: Specific acute toxicity values not established. No data available.

Skin Corrosion/Irritation: May cause mechanical skin irritation.

Serious Eye Damage/Irritation: Dust may cause mechanical eye irritation.

Respiratory or Skin Sensitization: Not available.

Germ Cell Mutagenicity: Not available.

Carcinogenicity: Not identified as a probable, possible, or confirmed human carcinogen by IARC,
ACGIH, NTP, or OSHA based on available data.

Reproductive Toxicity: Not available.

12. Ecological Information

Ecotoxicity: No data available regarding toxicity to fish, daphnia, or other aquatic
invertebrates.

Persistence and Degradability: Not available.

Bioaccumulative Potential: Not available.

Mobility in Soil: Not available.

13. Disposal Considerations

Waste Disposal Methods: Offer surplus and non-recyclable solutions to a licensed disposal
company. Dispose of in accordance with local, regional, national, and international regulations.

Contaminated Packaging: Dispose of as unused product.

14. Transport Information

DOT (US): Generally not regulated as dangerous goods based on available information. Supplier to
confirm.

IMDG: Not regulated as dangerous goods.

IATA: Not regulated as dangerous goods.

15. Regulatory Information

Safety, Health and Environmental Regulations: This product is typically used for research
purposes and is not subject to specific stringent hazardous substance regulations under standard listings.
Supplier to confirm status under TSCA, REACH, or local equivalent chemical inventories.

16. Other Information

Revision Date: 2026-04-18

Disclaimer: The information provided in this document is believed to be correct but does not
purport to be all-inclusive and shall be used only as a guide. The information is based on the present state of
knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent
any guarantee of the properties of the product.